I touched on Profhilo briefly when I compared it to Seventy Hyal and polynucleotides, but it gets asked about so often that it deserves its own proper explanation. So today, the full picture - what it is, how I inject it, and why it works the way it does.
It's not a filler, even though it's HA
Profhilo is hyaluronic acid at 64mg per 2ml syringe - the highest concentration of any HA product on the market. But where a filler is cross-linked to hold its shape and add volume, Profhilo uses NAHYCO® Hybrid Technology, a mix of high and low molecular weight HA that's designed to spread through the tissue rather than sit still.
That spreading is the whole point. As it moves through the skin, it stimulates your own fibroblasts to produce collagen and elastin, while also drawing in water to hydrate at a deeper level. You're not adding volume, you're prompting your skin to rebuild its own structure.
The BAP technique: why where I inject matters
Profhilo is injected using the Bio Aesthetic Points (BAP) technique — five precise points on each side of the face, ten in total, with 0.2ml placed at each one. That's the entire 2ml syringe used across those ten points.
This isn't arbitrary. The BAP points are chosen at specific anatomical locations that allow the product to diffuse evenly across the treatment area with minimal injections. Practically, that means:
Fewer needle entries than older techniques, so less soreness and swelling
More even spread and more predictable results
A quicker appointment, which clients always appreciate
Technique matters here as much as the product itself, this only works well when the points are right.
What to expect, treatment by treatment
The initial course is two sessions, four weeks apart. That gap isn't just scheduling - the first treatment gets fibroblast activity going, and the second one, four weeks later, builds on that response rather than starting from scratch. You don't get the full effect from one session alone.
Results build gradually over that course rather than appearing overnight, and most clients see the benefit lasting around six months before a top-up is worth considering. Depending on how your skin is ageing, some clients settle into repeating the full course roughly twice a year as maintenance.
Who it actually suits
Profhilo is my go-to when the main concern is laxity, crepiness, or an overall loss of firmness - it shows up most in the lower face, neck and jawline, areas where skin has started to lose its own structural support rather than just looking tired or dehydrated.
If your skin looks more dull or dehydrated than lax, Seventy Hyal is usually the better starting point. If it's more about texture, scarring or genuine repair, polynucleotides tend to do more for you. Profhilo's lane is firmness and structure - and within that lane, it's very good at its job.
Liz Founder, Novauria Aesthetics
Wondering if Profhilo is right for your skin? Book a free consultation — no pressure, just an honest chat.